*The EHI was validated using endoscopy-paired serum samples from 195 adult CD patients from a US-based tertiary care center. Validation cohort included patients with a longer-term disease duration who may have failed more than 1 biologic or had IBD-related surgeries. The EHI Score is intended to aid in the assessment of endoscopic disease activity in adult CD patients in conjunction with clinical evaluation performed by a healthcare professional. The Monitr test is not intended to diagnose CD.
†Endoscopically active disease defined as Crohn’s Disease Endoscopic Index of Severity (CDEIS) ≥ 3, Simple Endoscopic Score for Crohn’s Disease (SES-CD) > 2, or SES-CD = 2 (if only 1 intestinal segment had a score of 2 and scores of 0 in remaining segments).
1. D’Haens G, Kelly O, Battat R, et al. Development and validation of a test to monitor endoscopic activity in patients with Crohn’s disease based on serum levels of proteins. Gastroenterology. 2020;158(3):515-526.e10.