A comprehensive Crohn's disease assessment tool

A comprehensive Crohn's disease assessment tool

In Crohn's disease patient management, mucosal healing is known to be an objective measure of therapeutic response.1 This is likely due to the fact that in multiple clinical trials, mucosal healing is a therapeutic goal that has been associated with improved long-term outcomes in Crohn's disease patients.1-4

However, current mucosal healing assessment methods can make it challenging to:

  • Noninvasively evaluate the status of mucosal healing5,6
  • Assess active disease in difficult-to-reach locations, including the small bowel1,4,6
  • Obtain objective results for individual patients5
  • Regularly monitor mucosal healing5
 

Measure and monitor mucosal healing status with 1 noninvasive test

The PROMETHEUS® Monitr™ Crohn's Disease Test is a laboratory-developed test that provides critical information that helps you:


Establish a baseline measurement of disease activity at initial presentation

Track and assess disease activity and response to therapeutic management

Optimize your treatment plan

Evaluate if treatment changes may be appropriate

Counsel patients about therapeutic management goals

Reinforce importance of patient compliance to continue therapy

A powerful monitoring tool for Crohn's disease patients.

Easy to order: To request a Monitr Test Requisition Form, call Client Services toll-free in the U.S. at 888-423-5227 (Monday through Friday from 6 AM to 4:30 PM PST) or visit www.prometheuslabs.com.

References

References:
  1. 1.De Cruz P, Kamm MA, Prideaux L, Allen PB, Moore G. Mucosal healing in Crohn's disease: a systematic review. Inflamm Bowel Dis. 2013;19(2):429-444.

  2. 2.Frøslie KF, Jahnsen J, Moum BA, Vatn MH; IBSEN Group. Mucosal healing in inflammatory bowel disease: results from a Norwegian population-based cohort. Gastroenterology. 2007;133(2):412-422.

  3. 3.Rutgeerts P, Van Assche G, Sandborn WJ, et al. Adalimumab induces and maintains mucosal healing in patients with Crohn's disease: data from the EXTEND trial. Gastroenterology. 2012;142(5):1102-1111.

  4. 4.Shah SC, Colombel JF, Sands BE, Narula N. Systematic review with meta-analysis: mucosal healing is associated with improved long-term outcomes in Crohn's disease. Aliment Pharmacol Ther. 2016;43(3):317-333.

  5. 5.Freeman HJ. Limitations in assessment of mucosal healing in inflammatory bowel disease. World J Gastroenterol. 2010;16(1):15-20.

  6. 6.Bryant RV, Winer S, Travis SP, Riddell RH. Systematic review: histological remission in inflammatory bowel disease. Is ‘complete' remission the new treatment paradigm? An IOIBD initiative. J Crohns Colitis. 2014;8(12):1582-1597.