Goes beyond just inflammatory processes

In developing the PROMETHEUS Monitr Crohn's Disease Test, Prometheus evaluated numerous factors that are related to mucosal damage and healing processes, including1:

  • Inflammatory bowel disease (IBD) biology
  • Relevant IBD signaling pathways
  • Therapeutic targets
  • Tumor biology
  • Classic wound healing

Monitr provides healthcare professionals with more information than inflammatory biomarkers alone. This innovative, laboratory-developed test features 13 biomarkers that are associated with mucosal damage and repair processes, including:

  • Inflammation: high-sensitivity C-reactive protein (hsCRP) and serum amyloid A 1 (SAA 1)
  • Cell adhesion: carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM 1) and vascular cell adhesion molecule 1 (VCAM 1)
  • Immune recruitment modulation: interleukin 7 (IL 7)
  • Growth factors (proliferation & repair): transforming growth factor α (TGFα)
  • Angiogenesis: angiopoietin 1 (Ang 1) and Ang 2
  • Matrix remodeling: matrix metalloproteinase 1 (MMP 1), MMP 2, MMP 3, MMP 9, and extracellular matrix metalloproteinase inducer (EMMPRIN)

Easy to order: To request a Monitr Test Requisition Form, call Client Services toll-free in the U.S. at 888-423-5227 (Monday through Friday from 6 AM to 4:30 PM PST) or visit www.prometheuslabs.com.


  1. 1.Data on file. Prometheus Laboratories Inc.